TREM2 regulates microglial cell activation in response to demyelination in vivo

ChEBI2015-07-06 更新2026-07-12 收录

胶质细胞调控

脱髓鞘疾病模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70475 数据链接链接失效反馈

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资源简介：

TREM2 regulates microglial cell activation in response to demyelination in vivo

创建时间：

2015-07-06

Activity dependent translation in astrocytes

胶质细胞调控

神经元活动依赖性翻译

Protein coding gene expression requires two steps â transcription and translation â which can be regulated independently to allow nuanced, localized, and rapid responses to cellular stimuli. Neur

NIAID Data Ecosystem120

List of primers.

婴儿期遗忘机制

胶质细胞调控

Infantile amnesia, the inability to recall episodic memories formed during early childhood, is a hallmark of postnatal brain development. Yet the underlying mechanisms remain poorly understood. This w

Figshare2026-01-20 更新50

A novel role of CDK2 inhibition in restraining microglial overactivation. A novel role of CDK2 inhibition in restraining microglial overactivation

胶质细胞调控

CDK2抑制剂

Neuroinflammation driven by microglial overactivation is a significant contributor across a diverse range of neurological disorders. While MEF2C mutations have been associated with a syndromic form of

NIAID Data Ecosystem30

AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation

阿尔茨海默病机制

胶质细胞调控

The hemizygous R47H variant of TREM2, a microglia-specific gene in the brain, increases risk for late-onset Alzheimer's disease (AD). Using transcriptomic analysis at the single-nuclei level from brai

NIAID Data Ecosystem50

Dynamics of reactive astrocytes fosters tissue regeneration after cuprizone-induced demyelination. Dynamics of reactive astrocytes fosters tissue regeneration after cuprizone-induced demyelination

脱髓鞘疾病模型

反应性星形胶质细胞

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50