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Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108 Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM, PIK-108 Authors: Hon, W.-C, Berndt, A, Williams, R.L. Deposit date: 2011-10-24 Release date: 2011-12-28 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Regulation of Lipid Binding Underlies the Activation Mechanism of Class Ia Pi3-Kinases. Oncogene, 31, 2012
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2011-10-24
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