Metagenomics of medieval ancients dental pulps from island of Corsican France.. Direct metagenomics of medieval ancients dental pulp from the 9th to 13th century archaeological site in Mariana, Corsica,

The dental pulp, trapping intact erythrocytes at the time of death, may offer a suitable material to document ancient intraerythrocytic pathogens such as Plasmodium parasites. Total DNA and proteins extracted from 33 dental pulp specimens collected from individuals exhumed in the 9th-13th century archaeological site in Mariana, Corsica were analyzed by open mind paleo-auto-immunohistochemistry and direct metagenomic and Plasmodium targeted immunochromatography assay.