Molecular machines in energy transduction, cellular signaling and defense processes

This BAG is composed of 6 working groups from 3 locations (universities of Cologne, Bochum, Duesseldorf),working with both MX and SAXS, the projectsfor this proposal are rather heterogeneous.
Nonetheless, our research focuses on six primary themes: proteins involved in transport processes, immune system function, disease association, industrial enzyme applications, light harvesting, and signaling or fixation processes.
Our research spans a wide range of biological processes, from membrane transport and pathogen defense to enzyme optimization for industrial and environmental applications. By obtaining high-resolution structures of these proteins, we aim to advance our understanding of their functions, paving the way for new therapeutic strategies, biotechnological innovations, and solutions to pressing environmental challenges.

本BAG由来自科隆大学、波鸿大学、杜塞尔多夫大学三个机构的6个工作组组成，相关团队同时开展MX与SAXS相关研究。本提案涉及的研究项目具有较强的异质性。尽管如此，我们的研究聚焦六大核心主题：参与转运过程的蛋白质、免疫系统功能相关蛋白、疾病关联蛋白、工业酶应用、光捕获过程以及信号传导或固定过程。我们的研究涵盖诸多生物学过程，从膜转运、病原体防御，到面向工业与环境应用的酶优化。通过解析这些蛋白质的高分辨率结构，我们旨在深化对其功能的认知，为新型治疗策略、生物技术创新以及应对紧迫环境挑战的解决方案铺平道路。