Source data for the diagnostic performance of delayed post gadolinium MRI descriptors across the range of MD clinical classifications

Case-controlled studies documenting the diagnostic performance of delayed post gadolinium MRI descriptors in distinguishing MD ears from asymptomatic ears or ears with other audio-vestibular conditions were identified (MEDLINE, EMBASE, Web of Science, Scopus databases: updated 17/2/2022). The meta-analysis included 66 unique studies and 3073 ears with MD, evaluating 11 MRI descriptors (in columns). The additional sheets pertain to the meta-regression. a)clinical classifications b) control group type (asymptomatic ear contralateral to MD v asymptomatic ears in other subjects v ear with other audio-vestibular condition) c) route of gadolinium administration (IV v IT) d) number of image reviewers (single v multiple observers) e) analysed on an ear basis v patient basis f) depiction of bone signal (intermediate v low) g) low risk of bias (any domain vs none) and high applicability (any vs none) h) study design (prospective v other and consecutive recruitment v other).

本研究检索并纳入了旨在评估延迟钆增强磁共振成像（Magnetic Resonance Imaging, MRI）描述指标鉴别梅尼埃病（Meniere's Disease, MD）患耳与无症状耳或合并其他前庭听觉疾病患耳的诊断性能的病例对照研究（case-controlled studies），检索数据库涵盖MEDLINE、EMBASE、Web of Science及Scopus，检索更新时间为2022年2月17日。本次荟萃分析（meta-analysis）共纳入66项独立研究，涉及3073例梅尼埃病患耳，对11项以表格列项呈现的MRI描述指标进行了评估。附加表格内容涉及荟萃回归分析（meta-regression），具体如下：
a) 临床分类
b) 对照组类型（梅尼埃病患耳的对侧无症状耳vs其他受试者的无症状耳vs合并其他前庭听觉疾病的患耳）
c) 钆对比剂给药途径（静脉注射（Intravenous, IV）vs鼓室内注射（Intratympanic, IT））
d) 影像阅片者数量（单阅片者vs多名观察者）
e) 分析维度：以耳为单位vs以患者为单位
f) 骨信号表现（中等信号vs低信号）
g) 偏倚风险等级（存在任一低偏倚风险域vs无低偏倚风险）及适用性等级（存在任一高适用性情况vs无高适用性情况）
h) 研究设计（前瞻性研究vs其他研究，连续招募受试者vs非连续招募受试者）