human cGAS catalytic domain bound with the inhibitor G108
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https://pdbj.org/mine/summary/6mju
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资源简介：
human cGAS catalytic domain bound with the inhibitor G108 Descriptor: 1-[6,7-dichloro-9-(1H-pyrazol-4-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Lama, L, Adura, C, Xie, W, Tomita, D, Kamei, T, Kuryavyi, V, Gogakos, T, Steinberg, J.I, Miller, M, Ramos-Espiritu, L, Asano, Y, Hashizume, S, Aida, J, Imaeda, T, Okamoto, R, Jennings, A.J, Michinom, M, Kuroita, T, Stamford, A, Gao, P, Meinke, P, Glickman, J.F, Patel, D.J, Tuschl, T. Deposit date: 2018-09-22 Release date: 2019-05-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nat Commun, 10, 2019
创建时间：
2018-09-22
