Genotyping data of 269 maize inbred lines

The data set includes genotyping data of 269 maize inbred lines developed from whole genome sequencing (WGS) data. Among them, WGS data of 254 lines are publicly available (https://doi.org/10.1093/gigascience/gix134). In addition, we generated WGS of 15 inbred lines that are resistant or susceptible to the bacterial maize disease Goss’s wilt. All WGS reads were trimmed and aligned to the B73 reference genome sequence (B73v3). Reads uniquely mapped to the reference genome were retained for variant calling. SNPs with the minor allele frequency higher than 5% and the genotyping missing data rate less than 30% were kept for genome-wide association mapping of genomic loci conferring Goss’s wilt resistance. SNP data were split to ten files each of which stores genotyping data for a chromosome.

本数据集涵盖269份玉米自交系的基因型数据，此类数据由全基因组测序（Whole Genome Sequencing, WGS）数据生成。其中254份自交系的全基因组测序数据已对外公开（链接：https://doi.org/10.1093/gigascience/gix134）。除此之外，本研究还针对15份对玉米细菌性病害戈斯萎蔫病（Goss’s wilt）具有抗性或感病性的自交系完成了全基因组测序。所有测序读段（reads）均经过修剪质控，并比对至B73参考基因组序列（B73v3）。仅保留唯一匹配至参考基因组的读段用于变异检出。后续筛选出次要等位基因频率高于5%、基因型缺失率低于30%的单核苷酸多态性（Single Nucleotide Polymorphism, SNP）位点，用于开展介导戈斯萎蔫病抗性的基因组位点的全基因组关联定位。最终将单核苷酸多态性数据拆分为10个文件，每个文件存储对应染色体的基因型数据。