Crystal Structure of beta secetase in complex with 2-amino-3-methyl-6-((1S, 2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3vv6
下载链接
链接失效反馈官方服务：
资源简介：
Crystal Structure of beta secetase in complex with 2-amino-3-methyl-6-((1S, 2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one Descriptor: 2-amino-3-methyl-6-[(1S,2R)-2-phenylcyclopropyl]pyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL, ... Authors: Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S. Deposit date: 2012-07-17 Release date: 2012-10-24 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode J.Med.Chem., 55, 2012
创建时间：
2012-07-17
