Abnormal histological findings - Female, 49 - Tissue image [7040247104962581]

This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 49Clinical description: Cervical dysplasia, HSILGender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedDiagnosis: Abnormal histological findingsResult of the histopathological examination: Foci of high-grade dysplasia (HSIL / CIN III), located near the transformation zone - IHC: p16 + (block reaction), increased Ki67 index,
present throughout the full thickness of the epithelium. Dysplastic changes do not reach the surgical margin of the endocervix. Features of mature and immature squamous metaplasia and a moderate chronic inflammatory infiltrate.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存入ZMDL-GUMED的子宫颈组织样本的组织病理学图像。该样本图像通过奥林巴斯VS200玻片扫描仪以20倍放大倍率拍摄，并保存为DICOM格式。
患者、样本及诊断详细信息如下：
1. 患者信息：年龄49岁，临床描述为宫颈发育异常、高级别鳞状上皮内病变（HSIL），性别为女性。
2. 诊断相关信息：诊断分类为ICD-10_10-20，分类编码为第十八章——其他未分类的症状、体征及临床和实验室异常发现；诊断结果为组织病理学异常发现。组织病理学检查结果显示：可见高级别发育异常病灶（HSIL/CIN Ⅲ），位于转化区附近；免疫组化（IHC）结果为p16阳性（整块染色反应），Ki67指数升高且累及上皮全层；发育异常病变未累及宫颈内口手术切缘，可见成熟及未成熟鳞状上皮化生，伴中度慢性炎症浸润。
3. 样本相关信息：样本材质为福尔马林固定石蜡包埋（FFPE），采集方式为手术标本，解剖部位为女性生殖器官，所属器官为子宫颈，组织类型为宫颈外口；染色类型为阳性/HE，染色方式无适用项，抗体无适用项。
4. 成像技术参数：成像设备为奥林巴斯VS200，镜头倍率为20倍，数据来源机构为格但斯克医科大学。