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TCR repertoires study in Inhibitory IL-10+CD4+ T-cells developed during cytomegalovirus chronicity

NIAID Data Ecosystem2026-05-01 收录

T细胞受体多样性

巨细胞病毒

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP387019 数据链接链接失效反馈

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资源简介：

deep TCRalpha and TCRbeta complementarity-determining region (CDR3) repertoire profiling for the Thy1.1pos (IL-10pos) and Thy1.1neg (IL-10neg) CD4 T-cells sorted from salivary glands of IL-10-reporter mice infected with MCMV

应用场景：

创建时间：

2023-07-11

系统性红斑狼疮

巨细胞病毒

ABSTRACT Introduction: In contrast to organ transplantation, few studies correlate the monitoring of pp65 antigenemia with a diagnosis of cytomegalovirus (CMV) in patients with systemic lupus erythema

DataCite Commons2020-08-29 更新70

Proportions of negative conversion of cytomegalovirus antigenemia among male and female patients with autoimmune diseases and non-autoimmune diseases at Peking Union Medical College Hospital, Beijing (2008 to 2018).

巨细胞病毒

自身免疫疾病感染监测

Proportions of negative conversion of cytomegalovirus antigenemia among male and female patients with autoimmune diseases and non-autoimmune diseases at Peking Union Medical College Hospital, Beijing

NIAID Data Ecosystem60

Mucosal and Parenteral Vaccination against Acute and Latent Murine Cytomegalovirus (MCMV) Infection by Using an Attenuated MCMV Mutant

巨细胞病毒

黏膜免疫机制

We used a live attenuated murine cytomegalovirus (MCMV) mutant to analyze mechanisms of vaccination against acute and latent CMV infection. We selected MCMV mutant RV7 as a vaccine candidate since thi

PubMed Central50

Table_1_Preimmune Control of the Variance of TCR CDR-B3: Insights Gained From Germline Replacement of a TCR Dβ Gene Segment With an Ig DH Gene Segment.XLSX

T细胞受体多样性

免疫基因组编辑

We have previously shown that the sequence of the immunoglobulin diversity gene segment (DH) helps dictate the structure and composition of complementarity determining region 3 of the immunoglobulin h

NIAID Data Ecosystem60

Peripheral blood TCR clonotype diversity as an age-associated marker of breast cancer progression (blood). Peripheral blood TCR clonotype diversity as an age-associated marker of breast cancer progression (blood)

肿瘤免疫微环境

T细胞受体多样性

Immune escape is a prerequisite of tumor growth. We previously described a decline in intratumor activated GZMB+CD8+ T cells and T cell receptor (TCR) clonotype diversity in invasive compared to in si

NIAID Data Ecosystem50

TCR repertoires study in Inhibitory IL-10+CD4+ T-cells developed during cytomegalovirus chronicity

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