Top 10 kinases that show a protective response in hypoxia when inhibited.

The data were obtained using KIEN on the entire kinase inhibitor library. The coefficient βk, a measure of the protective impact of each kinase, was calculated and the kinases were ranked using this parameter in order to estimate the main kinases influencing the protective mechanisms against hypoxia. In bold we show kinases important for the response of both cell lines.Top 10 kinases that show a protective response in hypoxia when inhibited.