Project SCORE processed with CERES

This dataset is the result of 318 cancer cell lines screened with the genome-wide KY1.0/1.1 CRISPR KO library by the Sanger Institute, processed with the Achilles pipeline (except QC). The publication describing the experiment is "Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens," DOI 10.1038/s41586-019-1103-9.Readcounts were downloaded from https://score.depmap.sanger.ac.uk/downloads on 8 May 2019. Only cell lines annotated by the authors as passing both QC steps in Supplementary Table 1 were retained. Additionally, only cell lines for which the Broad has copy number data as of 10 May 2019 were retained.For more details on included files, see README