Easy Access to Fully Functionalized Chiral Tetrahydro-β-Carboline Alkaloids
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Easy_Access_to_Fully_Functionalized_Chiral_Tetrahydro_Carboline_Alkaloids/2662864
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资源简介：
A four-step synthetic route to fully substituted chiral tetrahydro-β-carbolines (THBCs) is described. Starting from the (R,S,S)-Friedel−Crafts/Henry adduct obtained from three-component coupling of an indole, nitroalkene, and aldehyde catalyzed by imidazoline-aminophenol−CuOTf, the (1S,3S,4R)-THBCs were readily synthesized in a three-step operation including reduction of the nitro-functionality and Pictet−Spengler cyclization.
创建时间：
2016-02-23
