POI Autonomic Nervous System Testing Dataset in Ovarian Follicle Function in Patients with Premature Ovarian Failure

Data from the Autonomic Nervous System Testing form
Study Description
No proven therapy to restore ovarian function and fertility is available to patients with karyotypically normal spontaneous premature ovarian failure. We know that one-half of these patients have primordial follicles remaining in the ovary, and these follicles can function intermittently. This is a diagnostic omnibus protocol that permits baseline clinical evaluation of patients with premature ovarian failure. The findings will determine patients' suitability for specifically focused therapeutic research protocols. Whole exome sequences (WXS), phenotype, and clinical data for a subset of patients are available in dbGaP repository. Women with karyotypically normal and spontaneous
primary ovarian insufficiency (premature ovarian
failure, premature menopause) between the ages of
18 and 42 years.