Probiotics Database (PBDB)

The Probiotics Database (PBDB) is a comprehensive bioinformatics resource that systematically collects and categorizes probiotic strains derived from diverse fermented food sources. Currently housing 1,730 well-characterized probiotic strains, the database features a structured classification system including production-related (768 strains), research-oriented (264 strains), environmental protection (22 strains), disease prevention and treatment (17 strains), and other specialized categories (659 strains). Designed as a dynamic knowledge platform, PBDB provides essential biological information to support research across human health, animal science, and agricultural applications, with regular updates to incorporate new discoveries. Beyond serving as a reference repository, the database enables advanced bioinformatics analyses to elucidate probiotic mechanisms and facilitates the computational prediction of novel probiotic candidates from unexplored microbial resources. By integrating empirical data with analytical tools, PBDB significantly enhances our capacity to understand, develop, and apply probiotic solutions across multiple scientific and industrial domains.

益生菌数据库（Probiotics Database, PBDB）是一款综合性生物信息学资源库，系统性收集并分类整理源自各类发酵食品的益生菌菌株。目前该库收录1730株经充分表征的益生菌菌株，采用结构化分类体系，涵盖生产相关类（768株）、研究导向类（264株）、环境保护类（22株）、疾病防治类（17株）及其他专项类别（659株）。作为动态知识平台，PBDB可提供关键生物学信息，支撑人类健康、动物科学与农业应用领域的相关研究，并定期更新以纳入最新研究发现。除作为参考知识库外，该数据库还支持高级生物信息学分析以阐明益生菌作用机制，同时助力从未开发微生物资源中通过计算预测新型益生菌候选菌株。通过整合实证数据与分析工具，PBDB极大提升了我们在多科学及工业领域理解、开发及应用益生菌解决方案的能力。

搜集汇总

背景与挑战

背景概述

Probiotics Database (PBDB) 是一个全面的生物信息学资源，专门收集和分类来自多种发酵食品的益生菌菌株，目前包含1,730个特征明确的菌株，并采用结构化分类系统（如生产相关、研究导向等类别）。该数据库旨在支持人类健康、动物科学和农业应用的研究，同时提供生物信息学分析工具以预测新益生菌候选，促进益生菌机制的探索和应用开发。