Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 7h (4-(1-methyl-5-oxopyrrolidin-3-yl)-N-propylbenzenesulfonamide)
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 7h (4-(1-methyl-5-oxopyrrolidin-3-yl)-N-propylbenzenesulfonamide) Descriptor: 4-[(3R)-1-methyl-5-oxopyrrolidin-3-yl]-N-propylbenzene-1-sulfonamide, Bromodomain-containing protein 4 Authors: Ilyichova, O.V, Scanlon, M.J, Thompson, P.E. Deposit date: 2020-02-15 Release date: 2020-02-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Substituted 1-methyl-4-phenylpyrrolidin-2-ones - Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors. Eur.J.Med.Chem., 191, 2020
创建时间：
2020-02-15
