Breathing therapy for patients with medically unexplained physical symptoms and dysfunctional breathing. A pilot and feasibility trial.

Medically unexplained physical symptoms (MUPS) are symptoms without an identifiable organic cause that lead to functional impairment. MUPS is highly prevalent in general practice consultations. This pilot trial aimed to investigate the effectiveness and feasibility of a 5-week breathing retraining program for patients meeting the criteria for MUPS.
The trial used a quantitative observational design with pre- and post-intervention measurements. Fifteen participants with MUPS and dysfunctional breathing (assessed by the Nijmegen Questionnaire) were recruited from two general practitioner offices. The intervention consisted of 5 weekly sessions including education on breathing physiology and weekly breathing exercises focused on nasal breathing and resonance breathing techniques.

The data set consist of measurements (Nijmegen Questionnaire, The Subjective Health Complaints Inventory, The Measure Yourself Medical Outcome Profile, End-tidal CO2, blood pressure, and heart rate variability) recorded pre-intervention, 1 week post intervention, and three months post-intervention.

医学无法解释的躯体症状（Medically unexplained physical symptoms, MUPS）指无明确器质性病因且导致功能受损的躯体症状，该类症状在全科诊疗中患病率极高。本先导试验旨在针对符合医学无法解释的躯体症状诊断标准的患者，探究为期5周的呼吸再训练方案的有效性与可行性。本试验采用定量观察性研究设计，设置干预前、干预后测量环节。研究从两家全科诊所招募了15名同时符合医学无法解释的躯体症状与功能性呼吸障碍诊断标准的受试者，其呼吸障碍通过奈梅亨问卷（Nijmegen Questionnaire）评估确认。干预方案包含5次每周开展的授课环节，内容涵盖呼吸生理学知识讲解，以及以鼻式呼吸、共振呼吸技术为核心的每周呼吸训练。本数据集包含干预前、干预后1周及干预后3个月时采集的多项测量数据，具体包括奈梅亨问卷、主观健康抱怨量表（Subjective Health Complaints Inventory）、自测医疗结局量表（Measure Yourself Medical Outcome Profile）、呼气末二氧化碳分压（End-tidal CO2）、血压及心率变异性（heart rate variability）。