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Asymmetric Synthesis of 3-Substituted Isoindolinones: Application to the Total Synthesis of (+)-Lennoxamine

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https://figshare.com/articles/dataset/Asymmetric_Synthesis_of_3_Substituted_Isoindolinones_Application_to_the_Total_Synthesis_of_Lennoxamine/3305779
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资源简介:
An anionic chiral auxiliary mediated asymmetric alkylation of carbamate 2 provides 3-substituted isoindolinones 4 in high ee. This methodology was used in the first asymmetric synthesis of (+)-lennoxamine.
创建时间:
2005-01-06
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