Sustained axon regeneration induced by a synergy of PTEN and SOCS3 deletion

ChEBI2011-10-27 更新2026-07-21 收录

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神经修复基因调控

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Sustained axon regeneration induced by a synergy of PTEN and SOCS3 deletion

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2011-10-27

Control of Axonal Growth and Regeneration of Sensory Neurons by the p110δ PI 3-Kinase

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信号通路

The expression and function of the 8 distinct catalytic isoforms of PI 3-kinase (PI3K) in the nervous system are unknown. Whereas most PI3Ks have a broad tissue distribution, the tyrosine kinase-linke

NIAID Data Ecosystem110

CELF RNA binding proteins promote axon regeneration in C. elegans and mouse through regulation of syntaxin

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RNA结合蛋白

Axon injury triggers dramatic changes in gene expression. While transcriptional regulation of injury-induced gene expression is widely studied, less is known about the roles of RNA binding proteins (R

NIAID Data Ecosystem80

Robust axonal regeneration occurs in the injured CAST/Ei mouse central nervous system

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中枢神经损伤修复

Axon regeneration in the central nervous system (CNS) requires reactivating injured neuronsâ intrinsic growth state and enabling growth in an inhibitory environment. Using an inbred mouse neuronal p

NIAID Data Ecosystem60

Post-translational modification of Sox11 regulates RGC survival and axon regeneration

神经科学

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The failure of adult CNS neurons to survive and regenerate their axons after injury or in neurodegenerative disease remains a major target for basic and clinical neuroscience. Recent data demonstrated

NIAID Data Ecosystem80

Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH

自噬

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Macroautophagy/autophagy is essential for maintaining cellular homeostasis through the degradation of organelles and proteins. It also has a prominent role in modulating aging. However, the role of au

DataCite Commons2021-05-08 更新70

Sustained axon regeneration induced by a synergy of PTEN and SOCS3 deletion

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