Characteristics of Studies Investigating CVM Related to ADT.

Abbreviations: LOE =  level of evidence; CVM =  cardiovascular mortality; ADT =  androgen deprivation therapy; CAB =  combined androgen blockade; GnRH =  gonadotropin-releasing hormone (leuteinizing hormone releasing hormone, LHRH); AA =  oral antiandrogens; RP =  Radical prostatectomy/Curative Treatment; RT =  radiation therapy; WW/AS =  watchful waiting(WW)/active surveillance (AS); HRs =  Hazard Ratios; RRs =  Risk Ratios; AMI =  Acute Myocardial Infarction; SD =  standard deviation; NA =  not applicable; CaPSURE  =  Cancer of the Prostate Strategic Urologic Research Endeavor; ICES =  Institute for Clinical Evaluative Sciences; NPCR =  National Prostate Cancer Register; SEER =  Surveillance, Epidemiology and End Results Medicare data; GPRD =  UK General Practice Research Database.
amean or median.
bcompared with WW/AS.
cThe HR/RR was directly given in the publication.
dCombined estimates from all types of ADT with random effects meta-analysis.
Characteristics of Studies Investigating CVM Related to ADT.