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Effect of Aurora-A knockdown on gene expression in murine CRC cell lines.

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE247046
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We aim to investigate the gene expression profile regulated by Aurora-A in murine CRC cell lines to identify genes that are either positively or negatively modulated by Aurora-A. Aurora-A was knocked down in CT26 and MC38 cells using lentiviral-mediated short hairpin RNA (lenti-shmaurka-1). Cells transduced with lenti-shGFP served as the control group. At 48 hours post-seeding, the Aurora-A knockdown cells were harvested, and the RNA was extracted for comparative gene expression profiling using RNA-seq.
创建时间:
2024-02-12
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