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(Pro)renin receptor inhibition reduces plasma cholesterol and triglycerides but does not attenuate atherosclerosis in atherosclerotic mice

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP308714
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Purpose: to clarify the transcriptomic changes in aortic arch of inhibiting the (pro)renin receptor using (P)RR G-ASOs Overall design: Aortic arch isolated from non treated 8 week-old LDLR-/- mice (0 week control), 8-week-old LDLR-/- mice that received saline treatment and fed with WTD for 4 weeks, and 8-week-old LDLR-/- mice that received (P)RR G-ASOs treatment and fed with WTD for 4 weeks
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2024-03-03
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