GA-4Y

GA-4Y investigates the impact of Lactobacillus acidophilus treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample GA-4Y:<br>G: Denotes the strain ST-104 of Clostridioides difficile.<br>A: Represents timepoint 1, indicating sampling before C. difficile infection.<br>4: Refers to the specific mouse number under investigation.<br>Y: Indicates the treatment administered, which in this case is Lactobacillus acidophilus.

GA-4Y 本数据集旨在探究嗜酸乳杆菌 (Lactobacillus acidophilus) 治疗对艰难梭菌 (Clostridioides difficile) 感染小鼠肠道菌群的影响。研究收集了感染后小鼠的粪便样本，采用英维特创 (Invitrogen) 平台进行样本处理，并在 Ion Torrent NGS 测序系统上完成测序。通过 Ion Reporter SW（16S 分析模块）开展数据分析，结果显示在感染后第1、3、6天，微生物类群的动态丰度发生显著改变，为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在潜力提供了研究依据。
样本GA-4Y的标识含义如下：<br>G：代表艰难梭菌菌株ST-104；<br>A：表示时间节点1，即艰难梭菌感染前的采样时点；<br>4：指代本次研究中的特定小鼠编号；<br>Y：表示所施加的干预措施，本研究中为嗜酸乳杆菌处理。