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Proteome analysis of transgenic 1D1a mice

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NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/pride/PXD034188
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T cells specifically recognize an antigen with a T cell receptor (TCR) consisting of α- and β-chain. The transgenic 1D1a mice were generated on the genetic background of the B10.D2(R101) line and expressed in their T cells the α-chain TCR (TCRα) specific to the allogeneic MHC molecule Н2-Kb. To evaluate effects of TCRα transgenesis on the qualitative and quantitative composition of plasma proteins, comparative proteome analysis was performed for both female and male transgenic 1D1a and wild-type B10.D2(R101) mice aged 3-, 6-, and 12-months.
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2023-05-10
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