Optimum Blue Light Exposure: A Means to Increase Cell-Specific Productivity in Chinese Hamster Ovary Cells

Raw Data for manuscript titled Optimum Blue Light Exposure: A Means to Increase Cell-Specific Productivity in Chinese Hamster Ovary Cells
This dataset was generated from experiments conducted in mini bioreactor cultures to investigate the effects of blue light illumination on mammalian cells. The study demonstrated an increase in cell-specific productivity (csp) of monoclonal antibodies under blue light exposure.

The dataset includes:
Growth data: Detailed cell growth metrics.
Monoclonal antibody titers: Measurements of antibody concentration.
Intracellular ROS measurements: Data on reactive oxygen species levels.
Cell cycle analysis: Distribution of cells across different phases.
QTOF measurements: Proteomic and metabolomic profiling to explore mechanisms behind csp enhancement.
All data are presented in tabular format, including means and standard deviations, providing precise numerical values. The dataset is organized by light intensity (W/m²) and light intervals (light/dark cycles) to facilitate analysis of the observed effects.

This repository offers a comprehensive resource for further exploration of light-mediated productivity enhancement in bioprocesses.

《最佳蓝光暴露：提升中国仓鼠卵巢细胞（Chinese Hamster Ovary Cells）细胞特异性生产力》研究手稿的原始数据集
本数据集源自小型生物反应器培养实验，旨在探究蓝光照射对哺乳动物细胞的影响。本研究证实，蓝光暴露可提升单克隆抗体的细胞特异性生产力（cell-specific productivity, CSP）。

本数据集包含以下内容：
生长数据：详尽的细胞生长指标。
单克隆抗体效价：抗体浓度检测数据。
细胞内活性氧（reactive oxygen species, ROS）检测数据：涵盖细胞内活性氧水平的相关结果。
细胞周期分析：细胞在各细胞周期时相的分布情况。
QTOF检测数据：用于探究细胞特异性生产力提升机制的蛋白质组学与代谢组学表征数据。

所有数据均以表格形式呈现，包含均值与标准差，提供精确的数值结果。本数据集按照光照强度（W/m²）与光照间隔（明/暗循环）进行分类整理，以便于对观测到的效应开展分析。

本数据集库为生物加工过程中光介导的生产力提升相关后续研究提供了全面的参考资源。