IL-37 protects against obesity-induced inflammation and insulin resistance

ChEBI2015-05-18 更新2026-07-21 收录

肥胖代谢炎症

胰岛素抵抗机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-58952 数据链接链接失效反馈

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资源简介：

IL-37 protects against obesity-induced inflammation and insulin resistance

创建时间：

2015-05-18

Proteomic Analysis of Livers from Fat-fed Mice Deficient in Either PKCδ or PKCɛ

代谢蛋白质组学

胰岛素抵抗机制

To investigate the mechanisms of lipid-activated protein kinase C (PKC) family, PKCδ or PKCɛ, involved in insulin resistance and fatty acid metabolism, we employed an in vivo adaptation of SILAC to ex

NIAID Data Ecosystem60

Hypermethylation of hepatic mitochondrial ND6 provokes systemic insulin resistance. Hypermethylation of hepatic mitochondrial ND6 provokes systemic insulin resistance

DNA甲基化

胰岛素抵抗机制

Purpose: To reveal the mechanism of mitochondrial DNA methylation in the progression of fatty liver and insulin resistance. Methods: Liver mitochondrial DNA bisulfite-sequencing of high-fat diet (HFD)

NIAID Data Ecosystem40

The Full Capacity of AICAR to Reduce Obesity-Induced Inflammation and Insulin Resistance Requires Myeloid SIRT1

免疫代谢

胰岛素抵抗机制

Chronic Inflammation is a key link between obesity and insulin resistance. We previously showed that two nutrient sensors AMP-activated protein kinase (AMPK) and SIRT1 interact to regulate macrophage

Figshare2016-01-19 更新30

Final AICAR Data

代谢调控研究

胰岛素抵抗机制

Raw data underlying the manuscript entitled "Effects of intravenous AICAR (5'-aminoimidazole-4-carboximide ribosie) administration on insulin signaling and resistance in premature baboons, Papio sp."

Figshare2018-11-28 更新50

Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner

胰岛素抵抗机制

内质网应激代谢调控

Progranulin (PGRN) has recently emerged as an important regulator for glucose metabolism and insulin sensitivity. However, the direct effects of PGRN in vivo and the underlying mechanisms between PGRN

Figshare2016-01-19 更新30

IL-37 protects against obesity-induced inflammation and insulin resistance

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