Supplementary material 2

The effect of mechanical ventilationA. Network maps for spontaneously breathing patients and those undergoing mechanical ventilation during physiological signal recording are presented. The graphs display the mean TE values (in bits) for each edge. Edges shown in red represent TEs that are significantly higher (P < 0.05) in one group compared to the other. Edge weighting corresponds to the magnitude of information flow. Abbreviations: HR, heart rate; RR, respiratory rate; SpO2, oxygen saturation.B. Comparison of TEs, Indegrees and Outdegrees between survivors and non-survivors, excluding patients who underwent mechanical ventilation. P-values were calculated using either Student’s t-test and Mann-Whitney U test based on distribution of data.

机械通气的影响
A. 本研究展示了生理信号记录期间，自主呼吸患者与接受机械通气患者的网络图谱。各图表呈现了每条边的平均传递熵（Transfer Entropy，TE）值（单位：比特）。红色边代表该组相较于另一组的TE值显著更高（P < 0.05）。边的权重对应信息流的大小。缩写说明：HR（heart rate，心率）、RR（respiratory rate，呼吸率）、SpO2（oxygen saturation，脉搏血氧饱和度）。
B. 本部分比较了排除接受机械通气患者后，存活组与非存活组之间的传递熵、入度与出度。根据数据分布特征，分别采用学生t检验（Student’s t-test）与曼-惠特尼U检验（Mann-Whitney U test）计算P值。