Deciphering the dynamic transcriptional and post-transcriptional networks of macrophages in the healthy heart and after myocardial injury. Mus musculus

Macrophage plasticity has been studied in vitro, but transcriptional regulation upon injury is poorly understood. In this study, we generated a data set for genome-wide transcriptome and miRNAome analysis of macrophages in the healthy heart and after myocardial injury. Overall design: Cardiac macrophages GFP+ cells were isolated from Cx3cr1GFP/+ knock-in mouse hearts in steady-state and at different post-injury stages.