Gene summary for Fgfr1
收藏DataCite Commons2020-09-19 更新2025-04-15 收录
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### Gene expression in the mandibular and maxillary arches _Fgfr1_ is expressed in the maxillary and mandibular mesenchyme at E10.5. At E12.5, it is expressed in the odontogenic and osteogenic mesenchyme of maxilla and mandible. At E14.5, Fgfr1 is expressed in the molar epithelium, the osteogenic mesenchyme of the mandible, and in the tongue. | E10.5 | E12.5 | E14.5 | |-------|-------|-------| | {width=280 height=214} | {width=280 height=214} | {width=280 height=214} | |  Mandibular and maxillary |  Osteogenic and odontogenic |  Masticatory muscles | | mesenchyme | mesenchyme |  Mandibular osteogenic | | | | mesenchyme, differentiated osteoblasts, | | | | Meckel’s cartilage, and tongue | | | |  Tooth mesenchyme | | | |  Tooth epithelium | #### Sources: - Aberg T et al., Dev Biol., 2004 Jun 1;270(1):76-93. - Orr-Urtreger A et al., Development. 1991 Dec;113(4):1419-34. - Bachler M et al., Mech Dev., 2001 Feb;100(2):313-6. - Unpublished data from [Chai's Lab, University of Southern California.](http://face.usc.edu/).
### 上下颌弓的基因表达
成纤维细胞生长因子受体1(Fgfr1)于胚胎发育第10.5天(E10.5)在上颌与下颌间充质(mesenchyme)中表达。在胚胎发育第12.5天(E12.5),其在上颌骨及下颌骨的牙源性(odontogenic)间充质与成骨源性(osteogenic)间充质中表达。在胚胎发育第14.5天(E14.5),Fgfr1表达于磨牙上皮(molar epithelium)、下颌骨成骨间充质以及舌组织中。
| E10.5 | E12.5 | E14.5 |
|-------|-------|-------|
| {width=280 height=214} | {width=280 height=214} | {width=280 height=214} |
|  上下颌间充质(mesenchyme) |  成骨源性(osteogenic)与牙源性(odontogenic)间充质(mesenchyme) |  咀嚼肌(masticatory muscles) |
| | |  下颌骨成骨间充质、分化成骨细胞(differentiated osteoblasts)、梅克尔软骨(Meckel’s cartilage)与舌 |
| | |  牙源性间充质(tooth mesenchyme) |
| | |  牙上皮(tooth epithelium) |
#### 数据来源:
- Aberg T 等,《发育生物学》,2004年6月1日;270(1):76-93.
- Orr-Urtreger A 等,《发育》,1991年12月;113(4):1419-34.
- Bachler M 等,《发育机制》,2001年2月;100(2):313-6.
- 美国南加州大学蔡氏实验室(Chai's Lab, University of Southern California)未发表数据,详见 http://face.usc.edu.
提供机构:
FaceBase (www.facebase.org)
创建时间:
2020-09-19



