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X-ray crystal structure of human TNKS in complex with a small molecule inhibitor

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4uuh
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X-ray crystal structure of human TNKS in complex with a small molecule inhibitor Descriptor: 1,2-ETHANEDIOL, 5-methyl-3-[4-(piperazin-1-ylmethyl)phenyl]isoquinolin-1(2H)-one, GLYCEROL, ... Authors: Oliver, A.W, Rajasekaran, M.B, Pearl, L.H. Deposit date: 2014-07-28 Release date: 2015-07-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Design and Discovery of 3-Aryl-5-Substituted-Isoquinolin-1- Ones as Potent and Selective Tankyrase Inhibitors Medchemcommm, 6, 2015
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2014-07-28
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