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Table S1 - Hepatitis C Virus Induced miR200c Down Modulates FAP-1, a Negative Regulator of Src Signaling and Promotes Hepatic Fibrosis

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https://figshare.com/articles/dataset/_Hepatitis_C_Virus_Induced_miR200c_Down_Modulates_FAP_1_a_Negative_Regulator_of_Src_Signaling_and_Promotes_Hepatic_Fibrosis_/770114
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Transcription profile of the chronic HCV liver. Total RNA was isolated from the liver biopsies and mRNA expression analysis was done using the Illumina HumanHT-12 v3 Expression BeadChips array that contains (48000) probe sets. Gene expression levels in the samples were normalized based on the 16s ribosomal RNAs and housekeeping gene expression. PARTEK analysis software was used to analyze the differential expression profile of the genes. Changes in gene expression level of 2-fold or more in the HCV samples compared with the normal controls with p value <0.05 (based on ANOVA analysis) were considered to be significant. Chronic HCV patients had greater than two fold increases in the expression of 785 genes and greater than 2 fold reduction in the expression of 533 genes. (PDF)
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2013-08-12
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