Crystal structure of human IRE1 cytoplasmic domains in complex with a sulfonamide inhibitor.
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of human IRE1 cytoplasmic domains in complex with a sulfonamide inhibitor. Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]-3-methylnaphthalen-1-yl}-2-chlorobenzenesulfonamide, ... Authors: Mohr, C. Deposit date: 2014-07-29 Release date: 2014-10-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Unfolded Protein Response in Cancer: IRE1 alpha Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability. Acs Med.Chem.Lett., 6, 2015
创建时间：
2014-07-29
