Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-039
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Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-039 Descriptor: 4-[5-[(4~{a}~{R},8~{a}~{S})-4-oxidanylidene-3-propan-2-yl-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(2-azanyl-2-oxidanylidene-ethyl)benzamide, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... Authors: Singh, A.K, Anthonyrajah, E.S, Brown, D.G. Deposit date: 2016-06-07 Release date: 2018-03-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
创建时间：
2016-06-07
