Processed_QC_approved_normalised_expr_ICGC-PCA

Processed (sequencing reads aligned to the GRCh37 reference genome with TopHat using Bowtie), QC-approved (FastQC and htseq-qa), annotated (Htseq-count) and normalised expression data from ICGC-PCA project used in "The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis" study (https://pubmed.ncbi.nlm.nih.gov/33477882/).

本数据集为ICGC-PCA项目的表达数据，该数据经如下流程处理后获得：通过Bowtie调用TopHat工具将测序读段比对至GRCh37参考基因组、经FastQC与htseq-qa完成质量控制验证、采用Htseq-count完成基因注释，并进行了表达量标准化。上述数据被应用于研究《前列腺癌发生与进展的转录组学图谱：整合分析》（原英文标题："The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis"），该研究的PubMed编号为33477882。