HERV transcriptional profile of the human urothelium1.

1Numbers of samples positive for the respective HERV out of 13 paired (malignant and non-malignant) patient samples. Samples were considered positive, when their corresponding signals exceeded the calculated cut-off value as described in Materials & Methods. Incidences are given by absolute numbers of samples and do not represent any quantitative assessment of HERV transcript levels.2UROtsa cells were used as model system of the normal human urothelium.3Tumor cell lines under investigation: RT112, T24/83, UMUC-3, HT1197.4HERV subgroups selected for quantification by qRT-PCR.5HERV subgroups that represent the urothelium-specific core HERV signature.