LncRNA/mRNA expression profiling for human normal arterial intimae and advanced atherosclerotic plaques

In microarray analysis, we have characterized the lncRNA and mRNA profiles in three advanced atherosclerosis samples and in three normal intima tissues. A total of 30,586 lncRNAs and 26,109 coding transcripts were detected by microarray analysis. The microarray profiling analysis not only provides new insights into the pathogenesis of atherosclerosis, but may also reveal new biomarkers for its diagnosis and treatment. In the study presented here, 6 human samples (3 normal arterial intimae and 3 advanced atherosclerotic plaques) were used to acquire expression profiles, which provide further insight into the pathologies of atherosclerosis.