Biological effects of the four potential PhoQ inhibitors.
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https://figshare.com/articles/dataset/_Biological_effects_of_the_four_potential_PhoQ_inhibitors_/418456
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(a)The Pyrophosphate Reagent detects autophosphorylation. IC50 represents the concentration of the potential PhoQ inhibitor needed to inhibit 50% of SF-PhoQc's autophosphorylation. Values are means ± standard deviations from 3 independent wells.
(b)The Luminescent Kinase Assay detects autophosphorylation. IC50 represents the concentration of the potential PhoQ inhibitor needed to inhibit 50% of SF-PhoQc's autophosphorylation. Values are means ± standard deviations from 3 independent wells.
(c)KD: Equilibrium Dissociation constant.
(d)CC50 represents the concentration of a potential PhoQ inhibitor that results in 50% cytotoxicity of Vero cells. The highest concentration tested is 200 µmol/L.
(e)Healthy human erythrocytes were used for the hemolysis assay, and the hemolytic activities of the four potential PhoQ inhibitors are shown at (e)25 µmol/L and
(f)100 µmol/L.
创建时间：
2011-08-10
