Microarray study of aldosterone-producing adenomas (APA) and their adjacent normal adrenal glands

Aldosterone-producing adenomas (APA) are heterogeneous. The objectives of this study were to compare the transcriptional profiles in APA and normal adjacent adrenal gland (AAG). This was done through the Illumina beadchip analysis of RNA from eight paired APA-AAG. Other tissues (phaeochromocytoma, cushing, and hyperplastic adrenals) were included as controls. RNA samples from eight primary hyperaldosteronism patients, each with a paired aldosterone-producing adenoma (APA) and normal adjacent adrenal gland (AAG) were used for this microarray analysis as published (https://doi.org/10.1210/jc.2011-2965). --------------------------------------- Authors state "we have not been able to locate the raw data".