Balanced Ependymoma

We propose to definitively characterise the somatic genetics of a number of pediatric malignant tumours including ependymoma, high grade glioma and central nervous system primitive neurectodermal tumours through generation of comprehensive catalogues of somatic mutations by high coverage genome sequencing.

本研究旨在通过对包括室管膜瘤、高级别胶质瘤和中枢神经系统原始神经外胚层瘤在内的多种儿童恶性肿瘤进行全基因组测序，生成全面的体细胞突变目录，从而对其体细胞遗传学进行明确的表征。