Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period

Heart growth in the pregnant patient helps maintain cardiovascular function while supporting the growing fetus. However, in some cases, the cardiovascular demand of pregnancy can trigger life-threatening conditions, including hypertensive disorders of pregnancy and peripartum cardiomyopathy. We previously developed a computational model that accounts for hormonal and hemodynamic interactions throughout pregnancy to uncover the mechanisms behind this heart growth. Here, we evaluated its breadth, applying it to normal and abnormal rat pregnancies and after delivery. This dataset includes supplemental data and tables that support our findings and accompany our manuscript

妊娠个体的心脏生长可维持心血管功能，同时为发育中的胎儿提供支持。然而在部分情况下，妊娠带来的心血管负荷可引发危及生命的病症，包括妊娠高血压疾病(hypertensive disorders of pregnancy)与围产期心肌病(peripartum cardiomyopathy)。此前我们开发了一款计算模型，可覆盖妊娠全过程中的激素与血流动力学（hemodynamic）相互作用，以阐明该心脏生长的背后机制。本研究中，我们对该模型的适用范围进行了评估，将其应用于正常与异常的大鼠妊娠场景，以及分娩后阶段。本数据集包含支撑本研究发现的补充数据与表格，随本研究手稿一同发布。