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Mtb TMK in complex with compound 36

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4unq
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Mtb TMK in complex with compound 36 Descriptor: 4-[(R)-methylsulfinyl]-2-oxo-6-[3-(trifluoromethoxy)phenyl]-1,2-dihydropyridine-3-carbonitrile, SODIUM ION, THYMIDYLATE KINASE Authors: Read, J.A, Hussein, S, Gingell, H, Tucker, J. Deposit date: 2014-05-30 Release date: 2015-06-24 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure Guided Lead Generation for M. Tuberculosis Thymidylate Kinase (Mtb Tmk): Discovery of 3-Cyanopyridone and 1,6-Naphthyridin-2-One as Potent Inhibitors. J.Med.Chem., 58, 2015
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2014-05-30
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