Efficient accumulation of PCBs in adipocytes during a 12-hour period.

Quantities of PCBs accumulated in differentiated rat adipocytes, expressed in nmol per unit of cellular protein and per unit of neutral lipids (NLs), after a dose of PCBs was added during 12 hours in the culture medium. Quantities of NLs, expressed in µmol per unit of cellular protein are also presented. Data represent the means of (i) three independent experiments ± SEM for conditions with one PCB congener alone, (ii) five independent experiments ± SEM for conditions with the cocktail of PCBs. There was no significant difference of PCB and NL concentrations between the three PCB congeners, whatever the kind of contamination, alone or in cocktail (p>0.05).Efficient accumulation of PCBs in adipocytes during a 12-hour period.