In the presence of rmMCP-6 and rmMCP-7 the endothelial cells invade the Geltrex®.

SVEC4-10 cells were cultured for 5 hours at 37°C on Geltrex® in the presence of rmMCP-6, rmMCP-7 or in the absence of tryptases. In the absence of rmMCP-6 or -7, most of the SVEC4-10 cells remained rounded (arrows) and few cells spread on the substrate (arrowheads). In the presence of rmMCP-6 or -7 almost all endothelial cells were spread on the substrate and were organized into tubes (asterisks). Additionally, the SVEC4–10 cells invaded the Geltrex® only in the presence of the tryptases.