Supplementary information files for What have we learnt from quantitative case reports of acute lateral ankle sprains injuries and episodes of ‘giving-way’ of the ankle joint, and what shall we further investigate?

Supplementary information files for article What have we learnt from quantitative case reports of acute lateral ankle sprains injuries and episodes of ‘giving-way’ of the ankle joint, and what shall we further investigate? <br> Lateral ankle sprains are a commonly incurred injury in sports. They have a high recurrence rate and can lead to the development of persistent injury associated symptoms. We performed a quantitative synthesis of published case reports documenting the kinematics of acute lateral ankle sprains and episodes of “giving-way” of the ankle joint to provide a comprehensive description of the mechanisms. A systematic literature search was conducted to screen records within MEDLINE® and EMBASE® . Additional strategies included manual search of specific journals as well as contacting researchers in relevant communities to retrieve unpublished data. Twenty-four cases were included in the quantitative synthesis; 11 from individual case reports and 13 from four separate case series. Two authors independently reviewed all articles and extracted ankle joint kinematic data. Excessive ankle inversion was the most pronounced kinematic pattern observed across all included cases, with a mean peak inversion angle of 67.5° (range 2.0 to 142) and a mean peak inversion velocity of 974°/s (range 468 to 1752). This was followed by internal rotation and plantar flexion, respectively. A homogeneous linear function revealed a mean inversion velocity across all cases of 337°/s (range 117 to 1400; R² =0.78; p&lt;0.0001).

《我们从急性踝关节外侧扭伤及踝关节‘打软腿’发作的定量病例报告中获得了哪些认知，又应开展哪些后续研究？》一文的补充信息文件

踝关节外侧扭伤是体育运动中常见的损伤类型，其复发率较高，且可引发持续性损伤相关症状。本研究针对已发表的、记录急性踝关节外侧扭伤及踝关节‘打软腿’发作运动学特征的病例报告开展定量综合分析，以全面阐明其损伤机制。

研究通过系统文献检索筛选MEDLINE®与EMBASE®数据库中的相关记录，并辅以手工检索特定期刊、联系相关领域研究者以获取未发表数据的补充检索策略。本次定量综合分析共纳入24个病例：其中11例来自单篇病例报告，13例来自4项独立的病例系列研究。由2名研究者独立完成所有文献的审阅与踝关节运动学数据的提取工作。

纳入的所有病例中，最显著的运动学特征为踝关节过度内翻：平均内翻峰值角度为67.5°（范围2.0°~142°），平均内翻峰值角速度为974°/s（范围468°/s~1752°/s）。紧随其后的运动学异常分别为踝关节内旋与跖屈。通过齐次线性函数分析，所有病例的平均内翻角速度为337°/s（范围117°/s~1400°/s；决定系数R²=0.78，p<0.0001）。