Response of human lymphoblastoid cells to HZE (iron ions) or gamma-rays

Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiated cells with cells exposed 24 hours previously to 1.67 Gy HZE (1 GeV/amu iron ions accelerated at the NASA Space Research Laboratory (NSRL) of Brookhaven National Laboratory) or 2.5 Gy 137Cs gamma rays. TK6 cells were mock irradiated or exposed to HZE or gamma-rays and RNA was harvested 24 hours later. 3 biological replicates were independently grown and harvested during three different runs at the NSRL. One replicate per array.

对人类淋巴母细胞TK6细胞进行转录组分析，对比模拟照射细胞与24小时前暴露于1.67 Gy HZE（由NASA太空研究实验室（NSRL）的布鲁克黑文国家实验室加速的1 GeV/amu铁离子）或2.5 Gy 137Cs伽马射线的细胞。TK6细胞经过模拟照射或暴露于HZE或伽马射线，24小时后收集RNA。在NSRL的三个不同运行中独立培养并收集了3个生物学重复样本。每个阵列对应一个重复样本。