Single-cell RNA sequencing data on primary samples from: Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia

This dataset includes single-cell RNA sequencing (scRNA-seq) data from primary AML (acute myeloid leukemia) samples. Libraries were produced using the 10X Genomics Chromium Single Cell 3ʹ Reagent Kits v3 and sequenced on an Illumina Novaseq 6000 system (Illumina). The dataset is available as raw sequencing reads (fastq; restricted access) or as an annotated matrix of scRNA count data (h5ad). Published in: Sandén et al, Nature Cancer, 2025: https://www.nature.com/articles/s43018-025-01054-6

本数据集包含来自原发性急性髓系白血病（acute myeloid leukemia, AML）样本的单细胞RNA测序（single-cell RNA sequencing, scRNA-seq）数据。文库构建采用10X Genomics Chromium单细胞3'端试剂试剂盒v3，测序在Illumina Novaseq 6000系统（Illumina）上完成。该数据集可获取的形式包括原始测序读段（fastq格式，受限访问），以及带有注释的单细胞RNA计数矩阵（h5ad格式）。