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Decreased cell stiffness facilitates cell detachment and cell migration from breast cancer spheroids in 3D collagen matrices of different rigidity (data)

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DataCite Commons2024-09-20 更新2025-04-17 收录
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https://zivahub.uct.ac.za/articles/dataset/Decreased_cell_stiffness_facilitates_cell_detachment_and_cell_migration_from_breast_cancer_spheroids_in_3D_collagen_matrices_of_different_rigidity_data_/13359398/1
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资源简介:
Quantitative data for article G Higgins, JE Kim, J Ferruzzi, T Abdalrahman, T Franz, MH Zaman,<br>Decreased cell stiffness facilitates cell detachment and cell migration from breast cancer spheroids in 3D collagen matrices of different rigidity. bioRxiv, 2020, <br><br>One Excel file with two spreadsheets:<br>* Spreadsheet 'Spheroids in 2 mgml C': Data for experiments in collagen matrix with 2 mg/ml collagen concentration<br>* Spreadsheet 'Spheroids in 4 mgml C': Data for experiments in collagen matrix with 4 mg/ml collagen concentration<br><br>Data in each spreadsheet includes mitochondrial MSD and intracellular fluidity at different delay times tau for cells at different distances from the cell spheroid, i.e. 0dc, 4dc and 6 dc (dc refers to cell diameter).<br><br>

本数据集为论文《细胞刚度降低促进乳腺癌细胞球从不同刚度三维胶原基质中脱离并迁移》的配套量化研究数据,该论文作者为G Higgins、JE Kim、J Ferruzzi、T Abdalrahman、T Franz、MH Zaman,发表于2020年的bioRxiv预印本平台。 本数据集包含1个Excel文件,内含2张工作表: * 工作表"Spheroids in 2 mgml C":对应胶原浓度为2 mgml的三维胶原基质中的实验数据 * 工作表"Spheroids in 4 mgml C":对应胶原浓度为4 mgml的三维胶原基质中的实验数据 每张工作表内收录的数据包含:距细胞球不同距离(即0dc、4dc及6dc,其中dc指代细胞直径)的细胞,在不同延迟时间τ下的线粒体均方位移(MSD, Mean Square Displacement)与胞内流动性数据。
提供机构:
University of Cape Town
创建时间:
2021-03-23
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