Supplemental Data: Variations in mineral prestrain, nanostructure, and microarchitecture play a role in intervertebral disc loading

Data related to the publication "Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading", Parmenter et al., 2024, https://www.biorxiv.org/content/10.1101/2024.08.19.608559v2
Full methodology described in the above publication.
Total data size = 41 GB
Data used for statistical analysis:
sCT_DVC_stats_data.csv : Data used for statistical analysis shown in Fig. 3 and Fig. 4
DIAD_stats_data.csv : Data used for statistical analysis shown in Fig. 6
WAXD processing code:
processing_folder_D-period.py : python code for measuring diffraction peak parameters
ctMapperGUI.py : python code for mapping WAXD parameters onto X-ray projection image

Example sCT and DVC dataset (sample 5):
162365_2560xy_2160z_pag100_us2p5_8bit.tif : reconstructed sCT image of sample under 1 N preload, 13 GB, recommend opening in imageJ
162366_2560xy_2160z_pag100_us2p5_8bit.tif : reconstructed sCT image of sample after 40 micron displacement, 13 GB, recommend opening in imageJ
162365_caudal_mindist4p5_mesh.inp : mesh of caudal VEP used for creating the DVC pointcloud, ABAQUS input file
162366_cranial_mindist4p5_mesh.inp : mesh of cranial VEP used for creating the DVC pointcloud, ABAQUS input file
162365_caudal_pointcloud.txt : caudal VEP pointcloud for DVC
162365_cranial_pointcloud.txt : cranial VEP pointcloud for DVC
dvc_162365_caudal.disp : DVC displacement results for caudal VEP, output from iDVC executable, can visualise in Matlab
dvc_162365_cranial.disp : DVC displacement results for cranial VEP, output from iDVC executable, can visualise in Matlab
dvc_162365_caudal_1-sw25.Lstr.csv : strain data for caudal endplate generated from disp file
sample5_caudal_step1.csv : strain data for caudal endplate
sample5_caudal_step1.csv : strain data for cranial endplate generated from disp file
sample5_force_readout.xlsx : force, displacement, time data readout from the mechanical testing rig during the experiment
sample5BinaryROIs.zip : binary images of regions used for microarchitecture analysis
sample5ROImsvalues.xlsx : microarchitecture values for regions of interest
Example correlative sCT and WAXD dataset (sample 16):
17565_2560xy_2160z_us1_8bit.tif : reconstructed sCT image, 13 GB, recommend opening in imageJ
17565_BinaryROI_tifs : binary image regions used for microarchitecture analysis
17567 002 dperiod map.png : 002 d-period mapped on X-ray projection
17567 002 width map.png : 002 peak width mapped on X-ray projection
17567_310_Peak_D-period_data.txt : 310 d-period for each beampath through the sample
17567_310_Peak_width_data.txt : 310 peak width for each beampath through the sample
17567_D-period_data_002.txt : 002 d-period for each beampath through the sample
17567_Width_data_002.txt : 002 peak width for each beampath through the sample
k11-17567.nxs : raw diffraction data (part 1), recommend opening in DAWN (both parts required)
k11-17567.zip : raw diffraction data (part 2), recommend opening in DAWN (both parts required)
k11-17567_processed_220722_184414.nxs : processed diffraction data, recommend opening in DAWN