Population Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate
收藏doi.org2025-03-24 收录
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http://doi.org/10.17632/p8cgvyz4sz.2
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资源简介:
Here are the input datasets for the paper "Population Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate"
SPred_total_all_pheno.csv is the file combining the S-PrediXcan results with COLOC results. Please note that CAU=EUR.
*_attempt_newBP.txt are the files used in Manhattan plot development to assign BP and CHR values.
coloc_*_results.zip are the coloc output files for each PAGE phenotype for that particular MESA model.
SigGenes_SPred_1e7.csv are the significant genes identified from S-PrediXcan that met the threshold P < 1.1e-7.
SigGenes_SPred_bonferroni.csv are the significant genes identified from S-PrediXcan that met the threshold P < 0.05/# of genes tested.
以下为论文《基于人口匹配转录组预测提高TWAS发现和验证率》所涉及的输入数据集:
SPred_total_all_pheno.csv文件是将S-PrediXcan结果与COLOC结果相结合的文件。请注意,CAU代表EUR。
*_attempt_newBP.txt文件用于曼哈顿图中BP和CHR值的分配。
coloc_*_results.zip文件是针对特定MESA模型的每个PAGE表型的coloc输出文件。
SigGenes_SPred_1e7.csv文件是从满足阈值P < 1.1e-7的S-PrediXcan中识别出的显著基因。
SigGenes_SPred_bonferroni.csv文件是从满足阈值P < 0.05/# of genes tested的S-PrediXcan中识别出的显著基因。
提供机构:
doi.org



