MOESM4 of DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis

Additional file 4: Table S1. Genes in Group I-IV; List of genes with number of GATC fragments within the presumptive regulatory region (2.5 kb upstream to 1.5 kb downstream of the transcriptional start sites (TSS)) displaying transitions between Pc-binding states (gain, loss or no-change transition between enriched, intermediate and depleted HMM states) in scrib 1 if compared to WT profiles, and changes in gene expression levels of the respective gene in scrib 1 to whose TSS the taGATC fragments had been mapped to. Group I (RNA – up regulated; Pc binding – gain); group II (RNA – down regulated; Pc binding – gain); group III (RNA – up regulated; Pc binding – loss); group IV (RNA – down regulated; Pc binding – loss); m1 (RNA – down regulated; Pc binding – loss and gain); m2 (RNA – up regulated; Pc binding – loss and gain).

附加文件4：表S1。第I~IV组基因；本列表收录的基因满足以下两项条件：其一，其推定调控区域（转录起始位点（Transcriptional Start Site, TSS）上游2.5 kb至下游1.5 kb范围内）的GATC片段数量，在scrib¹突变体与野生型（Wild Type, WT）特征谱对比中，存在多梳蛋白（Polycomb, Pc）结合状态的转换——即富集、中等、缺失的隐马尔可夫模型（Hidden Markov Model, HMM）状态间的获得、丢失或无变化转换；其二，taGATC片段已定位至其转录起始位点的对应基因，在scrib¹突变体中的基因表达水平发生改变。各组划分标准如下：组I（RNA表达上调；Pc结合获得）；组II（RNA表达下调；Pc结合获得）；组III（RNA表达上调；Pc结合丢失）；组IV（RNA表达下调；Pc结合丢失）；m1组（RNA表达下调；Pc结合同时发生获得与丢失）；m2组（RNA表达上调；Pc结合同时发生获得与丢失）。